ISBN: 9781071619742
Код товара 150281
The Integrated Stress Response: Methods and Protocols
ISBN: 9781071619742
Код товара 150281
21 661 ₽
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Если Вы закажете книгу до 17.01.2025, то мы привезём её ориентировочно 28.02.2025.
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Автор
Matějů Daniel, Chao Jeffrey A.
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Издатель
Springer
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Тип обложки
Hardcover
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Размеры
26.21 x 18.54 x 2.29 cm
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Год издания
2022
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Вес (г)
770
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ISBN
9781071619742
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Язык
ENG
О чём книга?
This volume provides an up-to-date collection of protocols describing some of the key methods to investigate the integrated stress response (ISR), a vital evolutionarily conserved mechanism that enables eukaryotic cells to adapt to stress conditions and alter their gene expression programs. The content of the book is split between techniques to analyze mRNA translation regulation and methods to analyze interaction networks and ribonucleoprotein (RNP) granules. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, The Integrated Stress Response: Methods and Protocols serves as an ideal guide to help accelerate research into the complex and fascinating biology of the ISR.
An Overview of Methods for Detecting eIF2' Phosphorylation and the Integrated Stress Response.- CRISPR-Based Screening for Stress Response Factors in Mammalian Cells.- Multiplexed Analysis of Human uORF Regulatory Functions during the ISR Using PoLib-Seq.
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