Therapeutic Applications of Dopamine D3 Receptor Function

ISBN: 9783031230608
Код товара 154684

Boileau

Therapeutic Applications of Dopamine D3 Receptor Function

Therapeutic Applications of Dopamine D3 Receptor Function

ISBN: 9783031230608
Код товара 154684

20 962 ₽

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  • Автор

    Boileau

  • Издатель

    Springer

  • Тип обложки

    Soft cover

  • Размеры

    235 x 155

  • Год издания

    2024

  • ISBN

    9783031230608

  • Язык

    ENG

  • Кол-во страниц

    275

О чём книга?

The CTBN volume Therapeutic Applications of Dopamine D3 Receptor Function reviews the state of the knowledge on the dopamine D3 receptor and its role in human behavior and disease (i.e.: neuropsychiatric illnesses including schizophrenia, mood disorders, Parkinson’s disease, restless legs syndrome, addictions and substance use disorders). The volume is written by leading experts across multidisciplinary areas (imaging, biobehavioral testing and clinical trials, preclinical models / molecular pharmacology) converging on the therapeutic implications / potential of the D3 receptor. The D3 dopamine receptor is a member of the D2-like family of G protein-coupled receptors. It was cloned and characterized almost 25 years ago. A key feature of the D3 dopamine receptor system, which has attracted considerable attention, is its anatomical localization remarkably restricted to the limbic circuitry. This has spurred the hypothesis that D3 involvement could contribute to the pathophysiology of neuropsychiatric disorders (or to some features of neuropsychiatric disorders), including but not limited to psychosis, addictions and substance abuse, mood and movement disorders.

Preface.- A Historic Review of the D3 Dopamine System from D3 Cloning to Clinical Trials in Schizophrenia and Drug Addiction.- Location, Location, Location: The Expression of D3 Dopamine Receptors in the Nervous System.- Recent Advances in Dopamine D3 Rec
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