Long Non-Coding RNAs in Cancer

ISBN: 9781071615836
Код товара 150986

Navarro

Long Non-Coding RNAs in Cancer

Long Non-Coding RNAs in Cancer

ISBN: 9781071615836
Код товара 150986

16 769 ₽

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Если Вы закажете книгу до 17.01.2025, то мы привезём её ориентировочно 28.02.2025.

  • Автор

    Navarro

  • Издатель

    Springer

  • Тип обложки

    Soft cover

  • Размеры

    254 x 178

  • Год издания

    2022

  • Вес (г)

    765

  • ISBN

    9781071615836

  • Язык

    ENG

  • Кол-во страниц

    387

О чём книга?

This volume presents techniques needed for the study of long non-coding RNAs (lncRNAs) in cancer from their identification to functional characterization. Chapters guide readers through identification of lncRNA expression signatures in cancer tissue or liquid biopsies by RNAseq, single Cell RNAseq, Phospho RNAseq or Nanopore Sequencing techniques; validation of lncRNA signatures by Real time PCR, digital PCR or in situ hybridization; and functional analysis by siRNA or CRISPR based methods for lncRNA silencing or overexpression. Lipid based nanoparticles for delivery of siRNAs in vivo, lncRNA-protein interactions, viral lncRNAs and circRNAs are also treated in this volume. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and practical, Long Non-Coding RNAs in Cancer aims to provide a collection of laboratory protocols, bioinformatic pipelines, and review chapters to further research in this vital field.

LncRNAs and Available Databases.- LncRNA as Cancer Biomarkers.- Bioinformatics Pipeline to Analyze lncRNA Arrays.- Boinformatic Pipelines to Analyze lncRNAs RNAseq Data.- Single Cell RNAseq Analysis of lncRNAs.- Measuring lncRNA Expression by Real Time PC
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