Tight Junctions in Inflammation and Cancer

2023

новинки

ISBN: 9789819924141
Код товара 155119

27 950 ₽

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Если Вы закажете книгу до 30.09.2024, то мы привезём её ориентировочно 11.11.2024.

Автор
Bhat
Издатель
Springer
Тип обложки
Hardback
Размеры
235 x 155
Год издания
2023
ISBN
9789819924141
Язык
ENG
Кол-во страниц
193

О чём книга?

This book provides an updated account of tight junctions of different epithelia and endothelia and addresses their anatomy, biochemistry, physiology, synthesis, assembly, and modulation. It also discusses the relationship between molecular structure, function, regulation, posttranslational modifications of tight junction proteins and their role in gut microbiota maintenance, epithelial-mesenchymal transition, and intestinal barrier dysfunction-associated disorders important for the progression of human cancers. This book presents the pathological alterations of tight junctions at the blood-brain barrier that intensify or even initiate neurological dysfunction. Further, it reviews the significance of tight junctions and tight junction proteins in cancer development, infectious diseases, allergic reactions, and autoimmune disorders. Lastly, it highlights strategies for modulating tight junctions to enhance drug availability and organ deposition. This book is immensely useful for basic, translational, clinical, and interdisciplinary cancer researchers, practicing oncologists, and immunologists.

Chapter 1. Inflammation and Cancer: Role of Tight Junctions.- Chapter 2. Regulation of tight junction by cadherin adhesion and its implication in inflammation and cancer.- Chapter 3. Tight junctions, epithelial-mesenchymal transition and cancer metastasis

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