Stem Cell-Based Therapy for Lung Disease

2019

ISBN: 9783030294021
Код товара 144180

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Автор
Burgess
Издатель
Springer
Тип обложки
Hardcover
Размеры
257 x 185 x 15
Год издания
2019
Вес (г)
634
ISBN
9783030294021
Язык
ENG
Кол-во страниц
259

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This book presents state-of-the-art pre-clinical models and clinical applications of stem-cell-based therapies applied to different lung diseases, with a special focus on the translation of bench data into clinical studies. Starting with the assumption that abnormal lung tissue repair and regeneration has emerged as the driving force underlying pathogenesis and progression in many lung diseases, it sheds new light on the potential of stem/stromal cells as drivers of repair and sources of reparative factors in the lung. The first part of the book offers an overview of stem cell types and mechanisms involved in lung development, homeostasis, repair and regeneration, and reveals the crucial role of the extracellular matrix within the lung microenvironment. In the second part, leading experts present the latest pre-clinical evidence and clinical applications of stem-cell-based therapies in a wide variety of lung diseases, ranging from COPD and lung fibrosis to other rare lung diseases. The last section discusses stem cell delivery systems and devices, such as aerosolised spray application. This book appeals to pneumologists, stem cell and matrix biologists, as well as bioengeneers with a special interest in regenerative medicine applied to pulmonary diseases.

1 Chronic lung pathologies that require repair and regeneration.- I Stem/stromal cells populations in the lung.- 2 Characterization of stromal/stem cells in the lung and translation of knowledge of stem/stromal cell population to human lung .- 3 Compariso

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