High-Throughput Screening Assays in Toxicology

2023

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ISBN: 9781071622155
Код товара 142434

16 769 ₽

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Если Вы закажете книгу до 12.09.2024, то мы привезём её ориентировочно 24.10.2024.

Автор
Zhu
Издатель
Springer
Тип обложки
Soft cover
Размеры
254 x 178
Год издания
2023
Вес (г)
411
ISBN
9781071622155
Язык
ENG
Кол-во страниц
200

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This second edition volume expands on the previous edition by exploring the latest advancements in high throughput screening (HTS) in toxicity studies by using in vitro, ex vivo, and in vivo models. This volume also covers the application of artificial intelligence (AI) and data science to curate, manage, and use HTS data. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, High Throughput Screening Assays in Modern Toxicology, Second Edition is a valuable resource for scientists pursuing chemical toxicology research. This book will aid scientists and researchers in translating new HTS techniques into standardized chemical toxicology assessment tools that can refine, reduce, and replace animal testing.

Cell-Based Assays to Identify ERR and ERR/PGC Modulators.- Mitochondrial Membrane Potential Assay.- Cell-Based hERG Inhibition Assay in a High-Throughput Format.- Identifying CAR Modulators Utilizing a Reporter Gene Assay.- Study Liver Cytochrome P450 3A4

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