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This book provides a state-of-the-art overview of key areas of subcellular aging research in human cells. The reader is introduced to the historical development and progress in biomedical aging research and learns, for example, about the role of microRNAs, circRNAs, mitochondria and extracellular vesicles in cellular senescence. The reader will also learn more about how gap junctions, the nuclear pore complex and the proteasome are affecting the ageing processes. In addition, novel therapeutic opportunities through modulation of cellular senescence are discussed. The book follows on from Parts I and II of Biochemistry and Cell Biology of Ageing (Volumes 90 and 91 of the Subcellular Biochemistry book series) by covering interesting and significant biomedical ageing topics not included in the earlier volumes. Comprehensive and cutting-edge, this book is a valuable resource for experienced researchers and early career scientist alike, who are interested in learning more about the fascinating and challenging question of why and how our cells age.
Chapter 1: Introduction: Progression of the Science of Ageing.- Chapter 2: Chromatin structure from development to ageing.- Chapter 3: The nuclear envelope in ageing and progeria.- Chapter 4: Mitochondrial DNA mutations and ageing.- Chapter 5: The Proteas
Lippincott® Connect Featured Title Purchase of the new print edition of this Lippincott® Connect title includes access to the digital version of the book, plus related materials such as videos and multiple-choice Q&A and self-assessments.
Join the nearly half a million students who have built...
Understand the fundamentals of the Wireshark tool that is key for network engineers and network security analysts. This book explains how the Wireshark tool can be used to analyze network traffic and teaches you network protocols and features. Author Vinit Jain walks you through the use of Wireshar...
1901. Night draws in.With the stealth of a spy vessel, the royal ship Azizye approaches the famous vistas of Mingheria. An emerald build of pink stone. The 29th state of the ailing Ottoman Empire.The ship carries Princess Pakize, the daughter of a deposed sultan, her doctor husband, and the Royal C...
This book gathers the revised and selected contributions to the 6th Dementia Lab Conference, D-Lab 2022, held on September 20-22, 2022, in Leuven. It describes original and innovative research on how design can contribute to the quality of life of people with dementia, their loved ones, and caregiv...
Now in a revised and expanded second edition, this concise, straightforward and clearly written text presents the latest information on the evaluation and management of common issues and conditions in pediatric endocrinology.
READ - USE THE POWER OF THE FORCE ... Our new Star Wars Darth Vader tee comes from the vintage READ posters by the American Library Association inspiring kids to read during the 80s and 90s. Product Details: Cotton/poly fitted tee, distressed, softened print, colour: vintage black, Size: Medium, Le...
The Economic and Financial Impacts of the COVID-19 Crisis Around the World: Expect the Unexpected provides an informed, research-based in-depth understanding of the COVID-19 crisis, its impacts on households, nonfinancial firms, banks, and financial market participants, and the effectiveness of the...